WNK-dependent phosphorylation of gephyrin tunes GABAA receptors at inhibitory synapses and modulates anxiety behavior

Proceedings of the National Academy of Sciences, Volume 123, Issue 35, September 2026. <br/>SignificanceEfficient synaptic transmission depends on signaling pathways that regulate the trafficking and stabilization of neurotransmitter receptors at synapses. Here, we identify a chloride-sensitive signaling pathway involving the kinase WNK1 and its …



Source link